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ムーンショット型研究開発事業 [目標7] 慢性炎症の制御によるがん発症ゼロ社会の実現

トップ > 論文・成果

論文・成果

令和5年度

  • Nishikawa H: Establishment of immune suppression by cancer cells in the tumor microenvironment. Proc Jpn Acad Ser B Phys Biol Sci. 100(2):114-122. 2024 (Corresponding Author).DOI: 10.2183/pjab.100.005
  • Kondo M, Kumagai S, Nishikawa H: Metabolic advantages of regulatory T cells dictated by cancer cells. Int Immunol 36(2):75-86 2024 (Corresponding Author).DOI: 10.1093/intimm/dxad035
  • Z. Zhu, T. Yasui*, X. Zhao, Q. Liu, S. Morita, Y. Li, A. Yonezu, K. Nagashima, T. Takahashi, M. Osada, R. Matsuda, T. Yanagida and Y. Baba; Engineering Interface Defects and Interdiffusion at the Degenerate Conductive In2O3/Al2O3 Interface for Stable Electrodes in a Saline Solution; ACS Appl. Mater. Interfaces, 15, 36866 (2023).DOI:22zf0127009h0001 10.1021/acsami.3c03603
  • A. Yokoi*, K. Yoshida, H. Koga, M. Kitagawa, Y. Nagao, M. Iida, S. Kawaguchi, M. Zhang, J. Nakayama, Y. Yamamoto, Y. Baba, H. Kajiyama and T. Yasui*; Spatial exosome analysis using cellulose nanofiber sheets reveals the location heterogeneity of extracellular vesicles; Nat. Commun., 14, 6915 (2023). DOI: 10.1038/s41467-023-42593-9
  • Yunye He , Masaru Koido , Yoichi Sutoh , Mingyang Shi , Yayoi Otsuka-Yamasaki , Hans Markus Munter ; BioBank Japan; Takayuki Morisaki , Akiko Nagai , Yoshinori Murakami , Chizu Tanikawa , Tsuyoshi Hachiya , Koichi Matsuda , Atsushi Shimizu , Yoichiro Kamatani ; , East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer disease, Nature Genetics, 2023, 55,;2129-2138.DOI:JP22zf0127009 10.1038/s41588-023-01569-7
  • T. Nishimura, N. Kakiuchi, K. Yoshida, T. Sakurai, T. R. Kataoka, E. Kondoh, Y. Chigusa, M. Kawai, M. Sawada, T. Inoue, Y. Takeuchi, H. Maeda, S. Baba, Y. Shiozawa, R. Saiki, M. M. Nakagawa, Y. Nannya, Y. Ochi, T. Hirano, T. Nakagawa, Y. Inagaki-Kawata, K. Aoki, M. Hirata, K. Nanki, M. Matano, M. Saito, E. Suzuki, M. Takada, M. Kawashima, K. Kawaguchi, K. Chiba, Y. Shiraishi, J. Takita, S. Miyano, M. Mandai, T. Sato, K. Takeuchi, H. Haga, M. Toi, S. Ogawa: Evolutionary histories of breast cancer and related clones,Nature 2023.620(7974):607-614 doi:10.1038/s41586-023-06333-9
  • Suma S, Suehara Y, Fujisawa M, Abe Y, Hattori K, Makishima K, Sakamoto T, Sawa A, Bando H, Kaji D, Sugio T, Kato K, Akashi K, Matsue K, Carreras J, Nakamura N, Suzuki A, Suzuki Y, Ito K, Shiiba H, Chiba S, Sakata-Yanagimoto M. Tumor heterogeneity and immune-evasive T follicular cell lymphoma phenotypes at single-cell resolution. Leukemia 2023, 38(2):340-350, doi: 10.1038/s41375-023-02093-7
  • Hirai T, Naito Y, Koyama S*, Nakanishi Y, Masuhiro K, Izumi M, Kuge T, Naito M, Mizuno Y, Yamaguchi Y, Kang S, Yaga M, Futami Y, Nojima S, Nishide M, Morita T, Kato Y, Tsuda T, Takemoto N, Kinugasa-Katayama Y, Aoshi T, Villa JK, Yamashita K, Enokida T, Hoshi Y, Matsuura K, Tahara M, Takamatsu H, Takeda Y, Inohara H, Kumanogoh A.. Sema6D forward signaling impairs T cell activation and proliferation in head and neck cancer. JCI Insight. 2024 Feb 8;9(3):e166349. doi: 10.1172/jci.insight.166349 

令和4年度

  • Kato S, Maeda Y, Sugiyama D, Watanabe K, Nishikawa H, Hinohara K:The cancer epigenome: non-cell autonomous player in tumor immunity. Cancer Sci. 2023 Mar;114(3):730-740. doi: 10.1111/cas.15681. Epub 2022 Dec 18.
  • 西川博嘉:もっとよくわかる!腫瘍免疫学発がん~がんの進展~治療がん免疫応答の変遷がストーリーでわかる. 西川博嘉/編 羊土社 2023年02月28日発行 B5判 167ページ ISBN 978-4-7581-2212-2
  • Kuroda Y, Matsuyama H, Kawasaki T, and Miyazaki K:Anomalous Fluctuations in Homogeneous Fluid Phase of Active Brownian Particles. Phys. Rev. Research 5, 013077 – Published 2 February 2023.Doi.org/10.1103/PhysRevResearch.5.013077
  • Oyama N,Koyama S, and Kawasaki T:What Do Deep Neural Networks Find in Disordered Structures of Glasses?. Front. Phys., 09 January 2023.Sec. Soft Matter Physics.Volume 10 – 2022.Doi.org/10.3389/fphy.2022.1007861.
  • Usui Y, Taniyama Y, ..., Matsuda K, Murakami Y, Spurdle AB, Matsuo K, Momozawa Y: Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer. N Engl J Med. 2023 Mar 30;388(13):1181-1190. doi: 10.1056/NEJMoa2211807.
  • Nasiri Kenari A,..., Hoshino A:Protocol for Plasma Extracellular Vesicle and Particle Isolation and Mass Spectrometry-Based Proteomic Identification. Methods Mol Biol. 2023:2628:291-300. doi: 10.1007/978-1-0716-2978-9_19.
  • Sakamoto Y, Sasaki K, Omatsu M, ...Obama K, Seno H, Iwai K:Differential involvement of LUBAC-mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation. J Pathol. 2023 Mar;259(3):304-317. doi: 10.1002/path.6042. Epub 2022 Dec 20.
  • Arasawa S, Takeda H, ...Yamashita T, Ueda Y, Marusawa H, Seno H.:Evolutional transition of HBV genome during the persistent infection determined by singlemolecule real-time sequencing. Hepatol Commun. 2023 Feb 27;7(3):e0047. doi: 10.1097/HC9.0000000000000047. eCollection 2023 Mar 1.
  • Nagao M, Fukuda A, Seno H.:The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system. Oncotarget. 2023 Jan 26:14:54-56. doi: 10.18632/oncotarget.28349.
  • Ueda T, Shiina S, Iriguchi S, ...Seno H, Nakatsura T, Tamada K, Kaneko S:Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells . Nat Biomed Eng. 2023 Jan;7(1):24-37. doi: 10.1038/s41551-022-00969-0. Epub 2022 Dec 12.
  • Okuma HS, Yoshida H, ...Thai Anh T, Kohsaka S, Mano H, Yonemori K, Nakamura K and Yatabe Y:Molecular pathology quality control in Southeast Asia: Results of a Multiregional Quality Assurance Study from MASTER KEY Asia. Cancer Sci. 2023 Jun;114(6):2664-2673. doi: 10.1111/cas.15790. Epub 2023 Mar 28.
  • Mizuno S, Ikegami M, Koyama T, ... , Osuga Y, Mano H and Kohsaka S:High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer. Mol Cancer Ther. 2023 Feb 1;22(2):227-239. doi: 10.1158/1535-7163.MCT-22-0302.
  • Kusakabe M, Taguchi A, Tanikawa M, ... Mano H and Osuga Y.:Cells with stem-like properties are associated with the development of HPV18-positive cervical cancer. Cancer Sci. 2023 Mar;114(3):885-895. doi: 10.1111/cas.15664. Epub 2022 Dec 9.
  • Kobayashi H, Makise N, Shinozaki-Ushiku A,... , Mano H and Tanaka S.:Dramatic response to entrectinib in a patient with malignant peripheral nerve sheath tumor harboring novel SNRNP70-NTRK3 fusion gene. Genes Chromosomes Cancer. 2023 Jan;62(1):47-51. doi: 10.1002/gcc.23089. Epub 2022 Aug 18.
  • Kage H, Shinozaki-Ushiku A, Ishigaki K,... , Mano H, Miyagawa K and Oda K.:Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan. Cancer Sci. 2023 Apr;114(4):1710-1717. doi: 10.1111/cas.15717. Epub 2023 Jan 17.
  • Ishino T, Kawashima S,... , Mano H, Ishihara S, Kato N, Kawazu M and Togashi Y.:Somatic mutations can induce a noninflamed tumour microenvironment via their original gene functions, despite deriving neoantigens.Br J Cancer. 2023 Apr;128(6):1166-1175. doi: 10.1038/s41416-023-02165-6. Epub 2023 Feb 2.